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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
WNK4
All Species:
24.24
Human Site:
Y1164
Identified Species:
59.26
UniProt:
Q96J92
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96J92
NP_115763.2
1243
134739
Y1164
K
K
E
I
E
D
L
Y
S
R
L
G
K
Q
P
Chimpanzee
Pan troglodytes
XP_508919
2382
250683
Y2102
K
H
E
I
E
S
L
Y
T
K
L
G
K
V
P
Rhesus Macaque
Macaca mulatta
XP_001095845
2384
250725
Y2104
K
H
E
I
E
S
L
Y
T
K
L
G
K
V
P
Dog
Lupus familis
XP_548082
1065
115874
G990
E
D
L
Y
S
R
L
G
K
Q
P
P
P
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q80UE6
1222
132391
Y1143
K
K
E
I
E
D
L
Y
S
R
L
G
K
Q
P
Rat
Rattus norvegicus
Q7TPK6
1222
132815
Y1143
K
K
E
I
E
D
L
Y
S
R
L
G
K
Q
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508024
2425
260713
Y2061
K
N
E
I
E
A
L
Y
Q
R
L
G
K
P
L
Chicken
Gallus gallus
XP_418141
1412
157310
Y1320
N
V
L
T
P
L
A
Y
I
E
L
L
L
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_685164
1541
169823
Y1461
K
Q
E
I
E
E
L
Y
K
R
I
G
K
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8S8Y9
568
65308
D493
L
R
E
S
Y
S
D
D
G
E
K
Q
S
S
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
30.6
30.5
76.9
N.A.
86.4
86.4
N.A.
27.4
34.9
N.A.
46.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
38.6
38.5
78.5
N.A.
89.2
88.9
N.A.
36.7
46.5
N.A.
57.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
66.6
6.6
N.A.
100
100
N.A.
66.6
13.3
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
80
20
N.A.
100
100
N.A.
66.6
20
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
30
10
10
0
0
0
0
0
0
0
% D
% Glu:
10
0
80
0
70
10
0
0
0
20
0
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
10
0
0
70
0
10
0
% G
% His:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
70
0
0
0
0
10
0
10
0
0
0
10
% I
% Lys:
70
30
0
0
0
0
0
0
20
20
10
0
70
0
0
% K
% Leu:
10
0
20
0
0
10
80
0
0
0
70
10
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
10
10
10
10
60
% P
% Gln:
0
10
0
0
0
0
0
0
10
10
0
10
0
30
0
% Q
% Arg:
0
10
0
0
0
10
0
0
0
50
0
0
0
0
10
% R
% Ser:
0
0
0
10
10
30
0
0
30
0
0
0
10
10
0
% S
% Thr:
0
0
0
10
0
0
0
0
20
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
30
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
10
0
0
80
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _